Most Difficult to Diagnosis in Pediatrics

Kawasaki Disease (KD) has been selected as the top one in 10 most difficult diseases to diagnosis by 500 pediatricians in Taiwan in 2010. The criteria for KD diagnosis is, high fever over than 5 days plus 4 out of 5 sysmptoms (red eyes, rash, strawberry tongue, unilateral swollen lymph node, and erythema/edema in extremities). However, as a systemic inflammation diseases that accompanied with high fever and rash, it's hard to distinguish KD from other common infectious diseases, like Enterovirus, Scarlet Fever and Measles. Also, except high fever, sometime the patient only shows one or two of the five symptoms during disease progressing, making the diagnosis even harder, and thus delays the proper treatment.


(cited from http://knowmedge.com/blog/medical-mnemonics-symptoms-of-kawasaki-disease/)


To prevent the potential risk of heart complication, Pharmigene has developed a kit for KD biomarker detection. This kit could help pediatricians to diagnose KD in earlier stage during disease progression.