List of Genetic Tests

Cardiovascular-related Genetic Test

Cardiovascular diseases (CVDs) are the number 1 cause of death globally, and it is the second cause of death in Taiwan. The risk factors in CVDs include high blood pressure (hypertension), diabetes, obesity, smoking, high cholesterol, aging, peripheral vascular occlusive diseases, excessive stress, continuous staying up late and no exercise habit. People with a family history of CVDs or those with the above risk factors are strongly recommended to have early detection. Cardiovascular-related genetic test will let you know about your risk of developing CVDs.

Target:ACE, AGT, MTHFR, PAI1

Bone-Health Genetic Test

Osteoporosis is a disease caused by loss of calcium in bones and fragile bones. In early stages of bone loss are usually asymptomatic; however, it is not until a bone fracture which may cause by a sudden bump or an accidentally fall that bone loss is detected. According to the investigation of the Taiwan Association of Gerontology and Geriatrics, it was found that one of nine above-65-year-people suffer from osteoporosis in Taiwan. Furthermore, one out of four females aged over 65 had osteoporosis and as for postmenopausal women, roughly 25% of whom suffered from osteoporosis. Therefore, the genetic test for proneness to osteoporosis allows you to understand your own bone health to prevent osteoporosis in advance.

Target:VDR, VDR(Apal), ESR

Cellular Antioxidant Capacity Genetic Test

The human body, in order to maintain the physiological functions in a normal condition, shall conduct various biochemical reactions that can come with several free radicals that are harmful to the body itself. In addition, environmental pollutants, personal bad habits, abuse of chemical substances and mental health will also induce excessive production of free radicals that cause damages to the cells and tissues or disable the functions of the organs. For instance, blood vessels become fragile, the brain cells age, immune system start to decline, cataracts, cancer and systemic aging. Cellular Antioxidant Capacity Genetic Test will let you know about your antioxidant ability.

Target:SOD2, MPO

Liver Detoxification-related Genetic Test

Toxins in human body are detoxified by liver, which metabolize toxic substances and then excrete urine, sweat or blood to reduce the damage caused by toxic/carcinogenic substances. By testing the ability of a liver's detoxification enzymes or the capability of activating metabolic reactions in body, accompanied with individualized health management, liver function and metabolism can be effectively enhanced.

Target:NQO1, CYP1A1, GSTM1, GSTT1

Alzheimer's Disease-related Genetic Test

Alzheimer's disease is the most common cause of Dementia, which is mainly due to the gradual loss of brain function. This may further affect the mental function and lead to incapable of living in daily life. Studies have shown that a susceptibility gene risk factor, APOE (Apolipoprotein E Gene), which APOE E4 will increase the risk of suffering from disease. Genetic tests can help you understand whether you are born with high-risk genes and find out defects in your lifestyle. This can help people immediately improve in living quality and prevent dementia, especially those with frequent memory loss or emphasizing health of cranial nerves.

Target:APOE

Skin Health-related Genetic Test

The human body must carry out many biochemical reactions in order to maintain normal physiological functions; meanwhile, free radicals are generated. Additionally, the external environment also induces the overproduction of free radicals in body. Skin aging is the most easily detected indicator of body damage caused by excessive free radicals. However, sunlight is another major cause of skin damage. The most serious symptom is skin cancer or skin photoaging. Other defects such as decreasing skin clarity and luster, caused by horny layer thickening and insufficient water content, or increasing wrinkles, resulting from the elasticity reduction. Through the skin health related genetic analysis, customers can choose the best care for your skin to effectively improve skin condition or slow the aging of it.

Target:SOD2, MPO, MMP1, MC1R

Type II Diabetes-related Genetic Test

Type 2 diabetes (formerly called non-insulin-dependent or adult-onset) is a chronic disease of metabolic abnormality which is mainly caused by poor body resistance to insulin. Genes, environmental factors, and individual lifestyle (eg., diet, exercise, etc.) can affect the age of outbreak and the progression of type 2 diabetes. Nevertheless, it is generally believed that type 2 diabetes is polygenic inheritance. If one parent has diabetes, the chance of having a child with diabetes is 20%. Furthermore, if both parents have diabetes, the possibility of having a child with diabetes is up to 40% or even 50%. It is strongly recommended that families with a history of diabetes have early detection.

Target:TCF7L2, HHEX, CDKAL1, SLC30A8

Alcohol Metabolism Ability-related Genetic Test

The reason why some people will blush after drinking is the lack of the enzyme ALDH2, which metabolize alcohol. This leads to the accumulation of acetaldehyde in body, which causes the blood vessels expand and blush on face. Alcohol is metabolized in the liver with 2 steps: (1) ethanol is metabolized to acetaldehyde; (2) acetaldehyde is metabolized to acetic acid. The enzyme ALDH2 is significant in the second step and determines the rate of alcohol metabolism in body. Among these chemicals, acetaldehyde is the first level of carcinogens listed by WHO; however, if it accumulates in body for a long time, the possibility of carcinogenesis will uplift. Through genetic tests, customers can understand the individual ability to metabolize alcohol and avoid the risk of suffering from cancer.

Target:ALDH2

Obesity-related Genetic Test

Obesity is often an important risk factor for many chronic diseases, such as diabetes, cardiovascular disease or cancer. Obesity can be classified as single genotype (or Mendelian type) and multi-genotype (or common type). The former is caused by a serious genetic mutation in the energy balance system, extremely rare but mostly of early-onset. The symptoms are usually more severe. The latter is the main cause of most obesity or overweight cases. It is caused by multiple genetic mutations, congenitally forming a physique that tends to gain weight, and by environmental factors and eating habits. Obesity-related genetic test will let you know about your tendency for obesity.

Target:ADRB2, ADRB3, UCP1

Folic Acid Activation-related Genetic Test

The inability to convert ingested folic acid into active folic acid in a body can cause the deficiency of folic acid. When a person is lack of folic acid, the generation of red blood cells can be affected, which may lead to macrocytic anemia. The symptoms of patients lacking folic acid are weakness, fatigue, difficulty in paying attention, irritability, headache, palpitations and tachypnea, etc. This may further increase the chance of miscarriage or premature birth, and the abnormal development of the fetal neural tube during pregnancy. Therefore, women of childbearing age must ensure the abundant intake of folic acid. In fact, the degree of inefficiency in activating folic acid can not only affect people’s chemical sensitivity but also the sensitivity of anaphylaxis; moreover, it can possibly result in clotting, stroke, anxiety, depression, high blood pressure, certain cancers, or even thyroid problems, etc. In addition, either the concentration of homocysteine, which is a high risk factor of suffering from cardiovascular diseases, in blood or the replication and repair of DNA, which are relevant to cancer or neural tube defects, can also be affected by lack of folic acid. Therefore, by testing and understanding the capacity of folic acid metabolism, customers can prepare for their own health management or diet plan.

Target:MTHFR, MTRR

Stress Resistance Ability-related Genetic Test

According to medical theories, pressure and negative emotions can stimulate human body to secrete excessive adrenaline. This may further lead to the increase of free radicals, which will attack chromosomes in the nucleus and have a chance to cause various diseases. Furthermore, pressure may cause vasoconstriction and spasm as well. In long term, it may lead to vascular sclerosis or stroke. From this perspective, the maladjustment of stress resistance not only leads to mental illness or emotional disorders, but cause stroke and cancer occur at earlier ages. Stress resistance ability-related genetic test will let you know about your stress resistance ability.

Target:5HTT, COMT