Warfarin Dose Prediction (PG 1639, 1075, 0430)

DNA Genetic Tests

 
Warfarin Dose Prediction (PG 1639, 1075, 0430) -  |

Warfarin Dose Prediction (PG 1639, 1075, 0430)

Relating to Drug: Warfarin


Product Features

  • Required only hours from blood sample to results.
  • Designed for easy operation & analysis.
  • Validated accuracy with 400+ patients samples* & DNA sequencing.
  • Protected by US, Europe & world wide patents.
Regulatory Status CE IVD
Taiwan IVD
Singapore IVD
US ASR

Detection

VKORC1 (-1639) Detection:
RT-PCR & TaqMan® based detection method: each sample requires only 1 PCR rxns for surveying of relevant subtypes of VKORC1 (-1639). GG, GA, & AA subtypes controls are developed to establish the position of GG, GA, & AA subtypes for analysis. Analysis is based on the position of the test sample verses the positions of each subtypes. A complete kit version is CE marked and has IVD approval from Department of Health, Taiwan.

CYP2C9*2 Detection:
RT-PCR & TaqMan® based detection method: each sample requires only 1 PCR rxns for surveying of relevant subtypes of CYP2C9*2 (c.430). CC, CT, & TT subtypes controls are developed to establish the position of CC, CT, & TT subtypes for analysis. Analysis is based on the position of the test sample verses the positions of each subtypes. A complete kit version is CE marked and has IVD approval from Department of Health, Taiwan.

CYP2C9*3 Detection:
RT-PCR & TaqMan® based detection method: each sample requires only 1 PCR rxns for surveying of relevant subtypes of CYP2C9*3 (c.1075). AA, AC, & CC subtypes controls are developed to establish the position of AA, AC, & CC subtypes for analysis. Analysis is based on the position of the test sample verses the positions of each subtypes.A complete kit version is CE marked and has IVD approval from Department of Health, Taiwan.

Many studies have demonstrated the important role of genetic variability of vitamin K epoxide reductase (VKORC1) and cytochrome P450 2C9 (CYP2C9) genes in determining the dose of warfarin that should be used when the oral anticoagulant is initiated. Individuals that use DNA tests to determine their genotypes of these two genes can use the test results with other information to reach quickly a stable therapeutic dose while reducing drug adverse reactions at the same time. ( visit WarfarinDosing.org URL:http://www.warfarindosing.org/Source/Home.aspx )

Product Performance

Warfarin Dose Prediction TableWarfarin Dose Prediction Test

TAGVKORC1CYP2C9Warfarin Dosing,