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DNA Genetic Tests: HLA-B*5801 Detection
- Required only hours from blood sample to results
- Designed for easy operation & analysis
- Validated accuracy with 600+ patients samples* & DNA sequencing
- Protected by US, Europe, & world wide patents
- CE Marked IVD Kit Product Sheet <download - A4 / Letter>
Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA-B*5801) and allopurinol induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing SJS/TEN significantly. |
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Table : HLA-B*5801 Typing |
Genomic DNA |
Sample # |
DNA Sequencing |
Pharmigene RT-PCR |
Ethnicity of Healthy Volunteers |
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Positive (+) |
Negative (-) |
Positive (+) |
Negative (-) |
Taiwan |
100 |
17 |
83 |
17 |
83 |
Thailand |
51 |
10 |
41 |
10 |
41 |
Indonesia |
51 |
2 |
49 |
2 |
49 |
Philippine |
49 |
4 |
45 |
4 |
45 |
India |
46 |
5 |
41 |
5 |
41 |
Vietnam |
49 |
8 |
41 |
8 |
41 |
Han Chinese |
170 |
37 |
133 |
37 |
133 |
Caucasian |
100 |
2 |
98 |
2 |
98 |
Total |
616 |
85 |
531 |
85 |
531 |
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HLA-B*5801 Test |
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HLA-B*5801 FastGel Test |
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- PCR Master Mix inc. SYBR Green
- HLA-B*5801 Detection Mix
- Internal Control Detection Mix
- Positive Control Templates
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Workflow |
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- PCR Master Mix
- HLA-B*5801 + Internal Control Mix
- Positive Control Templates
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Workflow |
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| Our HLA-B*5801 detection test is unable to distinguish the following rare allele types: HLA-B*5705, 5804, 5805, 5809, 5810, 5811, 5812, 5813, 5815, 5817, 5819, 5821, 5822, 5823, 5824, 5828 |
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