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DNA Genetic Tests: HLA-B*5701 Detection
- Required only hours from blood sample to results
- Designed for easy operation & analysis
Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA-B*5701) and Abacavir induced hypersensitivity reactions (HSR). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing HSR significantly. |
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Table : HLA-B*5701 Typing |
Genomic DNA |
Sample # |
DNA Sequencing |
Pharmigene RT-PCR |
Ethnicity of Healthy Volunteers |
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Positive (+) |
Negative (-) |
Positive (+) |
Negative (-) |
False + |
Taiwan |
62 |
0 |
62 |
0 |
62 |
- |
Thailand |
44 |
0 |
44 |
0 |
44 |
- |
Indonesia |
47 |
1 |
46 |
2 |
45 |
1 |
Philippine |
44 |
0 |
44 |
0 |
44 |
- |
India |
46 |
8 |
38 |
8 |
38 |
- |
Vietnam |
45 |
2 |
43 |
2 |
43 |
- |
Total |
288 |
11 |
277 |
12 |
276 |
1 |
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HLA-B*5701 Test |
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- PCR Master Mix inc. SYBR Green
- HLA-B*5701 Detection Mix
- Internal Control Detection Mix
- Positive Control Templates
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Workflow |
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