Linked-read Sequencing

  The Chromium Genome uses the power of Linked-Reads to fully resolve genic phasing, reveal structural variation and detect variants in previously inaccessible and complex regions of the genome. Low complexity and repetitive regions previously missed with short-read sequencing are now accessible.

 

Figure 1. Chromium System links reads in difficult regions that share a barcode with those in flanking confident regions to anchor them.

 

Table 1. Summary of Variant Classes Called and Phased Using the Chromium™ Genome Solution.

 

Table 2. Supernova Assembler on four human samples and five non-human samples