DNA Genetic Tests: HLA-B*1502 Detection
  • Required only hours from blood sample to results
  • Designed for easy operation & analysis
  • Validated accuracy with 4500+ patients samples* & DNA sequencing
  • Protected by US, Europe, & world wide patents
  • CE Marked IVD Kit
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Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA*B1502) and carbamazepine, phenytoin, & oxcarbazepine induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing SJS/TEN by as high as 1300 times.

Table 1: HLA-B*1502 Typing
Genomic DNA
Sample #
DNA Sequencing
Pharmigene RT-PCR
False +
Ethnicity of Healthy Volunteers
 
Positive (+)
Negative (-)
Positive (+)
Negative (-)
 
Taiwan
100
9
91
9
91
-
Thailand
51
7
44
7
44
-
Indonesia
51
17
34
21
30
4
Philippine
49
4
45
9
40
5
India
46
2
44
2
44
-
Vietnam
49
15
34
15
34
-
Taiwan Han Chinese
170
15
155
15
155
-
Caucasian
100
0
100
1
99
1
Total
616
69
547
79
537
10

HLA-B*1502 Test
  • PCR Master Mix inc. SYBR Green
  • HLA-B*1502 Detection Mix
  • Internal Control Detection Mix
  • Positive Control Templates


Workflow
HLA-B*1502
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HLA-B*1502 FastGel Test
  • PCR Master Mix
  • HLA-B*1502 + Internal Control Mix
  • Positive Control Templates



Workflow
HLA-B*1502 FastGel