DNA Genetic Tests: HLA-B*5801 Detection Required only hours from blood sample to results Designed for easy operation & analysis Validated accuracy with 600+ patients samples* & DNA sequencing Protected by US, Europe, & world wide patents CE Marked IVD Kit

Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA*B5801) and allopurinol induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing SJS/TEN significantly.

Table 1: HLA-B*5801 Typing
Genomic DNA	Sample #	DNA Sequencing		Pharmigene RT-PCR
Ethnicity of Healthy Volunteers		Positive (+)	Negative (-)	Positive (+)	Negative (-)
Taiwan	100	17	83	17	83
Thailand	51	10	41	10	41
Indonesia	51	2	49	2	49
Philippine	49	4	45	4	45
India	46	5	41	5	41
Vietnam	49	8	41	8	41
Taiwan Han Chinese	170	37	133	37	133
Caucasian	100	2	98	2	98
Total	616	85	531	85	531

HLA-B*5801 Test PCR Master Mix inc. SYBR Green HLA-B*5801 Detection Mix Internal Control Detection Mix Positive Control Templates Workflow   Package Insert <download>

HLA-B*5801 FastGel Test PCR Master Mix HLA-B*5801 + Internal Control Mix Positive Control Templates Workflow   Package Insert <download>