Pharmigene, Inc. - Pharmigene, Inc. - As a pioneer of genetic test in pharmacogenomics and clinical diagnosis all over the world.

Improve Lives

HLA-B*1502 allele screening before using Carbamazepine prevents Stevens-Johnson syndrome and toxic epidermal necrolysis in Asian populations.
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Health Care

Strong association between HLA-B*5801 and allopurinol induced Steven-Johnson syndrome and toxic epidermal necrolysis, TEN.
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Personalized Medicine

Single nucleotide polymorphisms in the VKORC1 & CYP2C9 allele have been associates with different warfarin dosage in asian populations and caucasian.
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CUSTOMIZED MANUFACTURING

Pharmigene, Inc. now offers customized services in the development of molecular diagnostic products. Our services include development, clinical validation, GMP/ISO set-up, ASR manufacturing, CE Mark registration.
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HLA-B*1502 Detection

HLA-B*1502 Detection

Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA-B*1502) and carbamazepine, phenytoin, & oxcarbazepine induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing SJS/TEN by as high as 1300 times.

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HLA-B*5801 Detection

HLA-B*5801 Detection

Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA-B*5801) and allopurinol induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing SJS/TEN significantly.

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HLA-B*5701 Detection

HLA-B*5701 Detection

Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA-B*5701) and Abacavir induced hypersensitivity reactions (HSR). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing HSR significantly.

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HLA-B*27 Detection

HLA-B*27 Detection

The presence of HLA-B*27 allele is strongly associated with ankylosing spondylitis (AS), a chronic inflammatory disease of the axial musculoskeletal system and a few other rheumatic disorders (Reiter's syndrome, acute anterior uveitis, and inflammatory bowel disease). HLA-B*27 testing is routinely used to screen for AS since ~90% of patients with AS have the HLA-B*27 allele. The geographical distr...

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